-Obstructive Sleep Apnea (OSA) is a potentially serious sleep disorder. It causes breathing to repeatedly stop and start during sleep. -Obstructive Sleep Apnea (OSA) isĀ when a blockage in your airway keeps air from moving through your windpipe while you’re asleep. The blockage and lack of airflow can cause your blood oxygen levels to drop, triggering a survival reflex in your brain that wakes you up just enough to breathe again. -Main sign of OSA is loud snoring during sleep.